, Events

MSB Seminar: Quantitative magnetic resonance imaging and spectroscopy of lipids

Speaker: Dominik Weidlich; PhD student at the Body Magnetic Resonance Research Group led by Prof. Dimitrios Karampinos

Time: 28 January, 1:00 pm

Place: Munich School of BioEngineering (Lecture Hall E.126, Boltzmannstr. 11, 85748 Garching)

Abstract: 
The metabolic syndrome is a cluster of conditions, including obesity and insulin resistance, that increases by two-fold the risk for developing cardiovascular disease (CVD) and by five-fold the risk for developing type 2 diabetes. The prevalence of the metabolic syndrome is estimated between 20% and 30% in the adult population of most countries. The selection of optimal strategies for preventing diabetes and CVD for each individual patient is problematic using currently available biomarkers. Quantitative MRI of different fat depots can assist in improving the metabolic phenotyping of patients with metabolic syndrome with the ultimate goal to improve the selection of optimal prevention strategies for each individual patient.

The Body Magnetic Resonance Research Group focuses on the following directions:

  • Development of quantitative MRI biomarkers to quantify fat content and fatty acid composition in different organs (liver, skeletal muscle, adipose tissue).
  • Development of diffusion MRS and MRI techniques to study diffusion properties of adipose tissue.
  • Development of non-invasive techniques to differentiate between brown and white adipose tissue.
  • Development of efficient algorithms for the segmentation of the different abdominal fat depots.
  • Application of the developed techniques in longitudinal lifestyle intervention studies involving diet and physical exercise.