MIBE Online Seminar: Advanced Acquisition, Reconstruction and Quantification Methods for Magnetic Resonance Spectroscopy and Spectroscopic Imaging.

Titel: Advanced Acquisition, Reconstruction and Quantification Methods for Magnetic Resonance Spectroscopy and Spectroscopic Imaging

Sprecher: Jorge Coello Uribe (Gleich Group)

Datum und Uhrzeit: Mittwoch, 17. November, 12:00 Uhr

Abstract: In recent years, advances in medical imaging technologies like Magnetic Resonance (MR) Imaging have demonstrated their potential to positively impact the diagnosis and treatment of diseases, improving the life quality of individuals. Specifically, two modalities that are particularly interesting for clinical applications are MR Spectroscopy (MRS) and Spectroscopic Imaging (MRSI) capable of mapping the metabolic composition of tissues.
The present talk addresses the major challenges of this technique that limits access to MRS and MRSI examinations and their adoption in the medical practice. The work focuses on the development of optimized acquisition and reconstruction methods to achieve higher robustness, sensitivity, and speed. Thus, improving the reliability of the examinations and diagnoses made by the medical experts.
The obtained improvements in acquisition sequences, signal reconstruction, and signal enhancement will be presented. These major developments include: (i) A reconstruction framework that enabled accelerated brain MRSI with an improved signal quality, acquired in standard MR systems (3 Tesla) (ii) an MRSI methodology optimized for ultra-high magnetic fields (7 Tesla) that enabled high-resolution metabolite mapping, and (iii) machine learning methods for an improved signal quantification in MRS and MRSI.