Titel: Simulation of the Electric Excitability of Auditory Nerve Fibers Stimulated with Multipolar Cochlear Implant Electrode Configurations.
Sprecher: Jonas Geißdörfer, Hemmert Group
Datum und Uhrzeit: Dienstag, 08. Juni 2021, 13:00 Uhr
Abstract: Cochlear implants stimulate surviving auditory nerve fibers through electrical stimulation. We investigated stimulation applied in monopolar, bipolar and tripolar configuration. A 3D finite element cochlea model was employed to obtain potential data, which was subsequently fed to biophysical neuron population models. For bi- and tripolar stimulation, spatially more restricted electric fields, higher average thresholds and on average larger dynamic ranges were observed. With dendrite degeneration, average thresholds increased, while average dynamic ranges decreased. Near threshold, action potentials were initiated in fibers in proximity to the stimulation electrodes. For bi- and tripolar stimulation, with stimulation slightly above thresholds independent populations were excited.
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