Titel: Macromolecular Coatings for Endotracheal Tubes
Sprecherin: Bernardo Miller Naranjo, Doctoral Candidate (Lieleg Group)
Datum und Uhrzeit: Dienstag, 13. Juni 2023, 13:00 Uhr
Abstract: Endotracheal intubation is indispensable in modern healthcare but typically entails two complications for the treated patients: biofouling-induced infections and friction-associated damage to the tissue. Coatings on the endotracheal tubes (ETT) may mitigate those problems, but they require a well-defined testing method to assess their functionality. Here, such a testing setup is presented, which allows for conducting ex vivo extubation experiments in a reproducible manner. With this setup, different coating strategies that immobilize porcine gastric mucins on the ETT surface are compared. The results demonstrate that covalent coatings generated from lab-purified mucins outperform the other variants in terms of their ability to decrease tissue damage, prevent lipid adsorption, and reduce cell attachment. With a similar approach as presented here, it should also be possible to evaluate macromolecular coatings generated on other medical tubing systems such as cardiac and urinary catheters and endoscopes.
WEITERE INFORMATIONEN
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WEITERE TERMINE IM SOMMERSEMESTER 2023
20 June 2023 | 1:00 pm | Dr. Nako Nakatsuka | ETH Zürich | DNA Aptamer-Driven Neurochemical Biosensing |
27 June 2023 | 1:00 pm | N.N. | Doct. Cand. (Moretti) | tbd |
04 July 2023 | 1:00 pm | N.N. | Doct. Cand. (Schäfer) | tbd |
11 July 2023 | 1:00 pm | Aris Papargyriou | Doct. Cand. (Reichert) | tbd |
18 July 2023 | 1:00 pm | Doct. Cand. (Hebrok/Reichert) | tbd |