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MIBE Seminar: Macromolecular Coatings for Endotracheal Tubes

Topic: Macromolecular Coatings for Endotracheal Tubes

Speaker: Bernardo Miller Naranjo, Doctoral Candidate (Lieleg Group)

Date and Time: Tuesday, 13 June 2023, 1:00 pm

Abstract: Endotracheal intubation is indispensable in modern healthcare but typically entails two complications for the treated patients: biofouling-induced infections and friction-associated damage to the tissue. Coatings on the endotracheal tubes (ETT) may mitigate those problems, but they require a well-defined testing method to assess their functionality. Here, such a testing setup is presented, which allows for conducting ex vivo extubation experiments in a reproducible manner. With this setup, different coating strategies that immobilize porcine gastric mucins on the ETT surface are compared. The results demonstrate that covalent coatings generated from lab-purified mucins outperform the other variants in terms of their ability to decrease tissue damage, prevent lipid adsorption, and reduce cell attachment. With a similar approach as presented here, it should also be possible to evaluate macromolecular coatings generated on other medical tubing systems such as cardiac and urinary catheters and endoscopes.

More information

The MIBE Seminar will take place in our lecture hall E.126 (Boltzmannstr. 11, 85748 Garching) and will be live streamed via zoom.

The zoom details for all online seminar talks this semester are:

Meeting Name: MIBE Seminar Talks, Tuesdays 1:00 pm

Meeting-ID: 698 5129 8624
Password: mibe

The MIBE Seminar counts as subject specific qualification for doctoral candidates.
Registration here.

Further Program Summer Term 2023

20 June 2023 1:00 pm Dr. Nako Nakatsuka ETH Zürich DNA Aptamer-Driven Neurochemical Biosensing
27 June 2023 1:00 pm N.N. Doct. Cand.
04 July 2023 1:00 pm N.N. Doct. Cand.
11 July 2023 1:00 pm Aris Papargyriou Doct. Cand.
18 July 2023 1:00 pm   Doct. Cand.