Titel: Organoid Models to Study Cellular Plasticity and Treatment Resistance in Pancreatic Cancer
Sprecher: Aris Papargyriou (Reichert Group)
Datum und Uhrzeit: Dienstag, 11. Juli 2023, 13:00 Uhr
Abstract: Organoid technologies have revolutionized the way we understand complex biological processes and model diseases such as cancer. Recently in our lab we developed a novel organoid model where we recapitulate branching morphogenesis of pancreatic tumours recapitulating the in vivo primary tumour architecture. In this talk we will discuss how we can take advantage of this system to understand cellular plasticity with emphasis to a conserved developmental program, the epithelial-to-mesenchymal transition. How this plasticity can shape inter- and intra-tumoral heterogeneity and how these two hallmarks of cancer contribute to treatment resistance.
WEITERE INFORMATIONEN
Das MIBE Seminar findet in Präsenz im Hörsaal E.126 (Boltzmannstraße 11, 85748 Garching) statt und wird zusätzlich live per zoom übertragen.
Zoom Daten für alle online Seminarvorträge in diesem Semester:
Meeting Name: MIBE Seminar Talks, Tuesdays 1:00 pm
https://tum-conf.zoom.us/j/69851298624?pwd=TURFMGQ5N3pDZ0ZGVkVHejFTMFJhUT09
Meeting-ID: 698 5129 8624
Password: mibe
Das MIBE Seminar kann für Promovierende als fachliche Qualifizierung angerechnet werden.
Registrierung hier.
WEITERE TERMINE IM SOMMERSEMESTER 2023
| 18 July 2023 | 1:00 pm | Isabel Aschenbrenner | Doct. Cand. (Feige) | Interleukin Engineering |