Titel: Scalable Tissue Clearing Technologies for Unbiased Study of Entire Organs and Organisms
Sprecher: Jennifer Modamio (Hebrok Group)
Datum und Uhrzeit: Dienstag, 14. Mai 2024, 13:00 Uhr
Abstract: Recent breakthroughs in tissue-clearing methodologies have transformed the study of intact tissues, organs, and organisms, offering a 3D visualization of interconnected systems at a single-cell resolution. These methods, integrated with light-sheet microscopy, AI-based analysis, and proteomics, streamline histological and molecular examinations, potentially reducing processing time and cost. The chemical processes enable whole-organ labeling, broadening the scope to include thick human tissues and facilitating comprehensive whole-body scanning of small mammalian models. By harnessing this synergy, researchers can rapidly extract comprehensive, multiscale insights from complex biological specimens. This seminar will provide an overview of cutting-edge tissue-clearing approaches, emphasizing the versatile DISCO protocols. Common implementation challenges and solutions will be addressed to equip attendees with the necessary knowledge to adopt these technologies seamlessly. Participants will gain valuable insights into using these technologies for unbiased, systems-level investigations spanning entire organs and organisms for an unprecedented understanding of biological processes to support disease research.
WEITERE INFORMATIONEN
Das MIBE Seminar findet in Präsenz im Hörsaal E.126 (Boltzmannstraße 11, 85748 Garching) statt und wird zusätzlich live per zoom übertragen.
Zoom Daten für alle online Seminarvorträge in diesem Semester:
Meeting Name: MIBE Seminar Talks, Tuesdays 1:00 pm
https://tum-conf.zoom.us/j/69851298624?pwd=TURFMGQ5N3pDZ0ZGVkVHejFTMFJhUT09
Meeting-ID: 698 5129 8624
Password: mibe
Das MIBE Seminar kann für Promovierende als fachliche Qualifizierung angerechnet werden.
Registrierung hier.
WEITERE TERMINE IM SOMMERSEMESTER 2024
May 28, 2024 Filipa Goncalves Westmeyer Group Title tbd
Jun 11, 2024 Florian Schaff Pfeiffer Group Title tbd
Jun 18, 2024 Henriette Bast Pfeiffer Group Title tbd
Jun 25, 2024 Dominik John Herzen Group Title tbd
Jul 09, 2024 Francesca Gasparin Ntziachristos Group Optoacoustic Microscopy
Ludwig Englert