• MSB-PI Vasilis Ntziachristos

    Radio feature about optoacoustic tomography (in German)

    German public radio (Deutschlandfunk) reported on the work of MSB-PI Vasilis Ntziachristos and his colleagues at the TUM professorship of Biological Imaging and the Institute for Biological and Medical Imaging at the Helmholtz Zentrum München.

  • Mechanism of new small molecule inhibitors for the treatment of depression, pain and obesity decoded

    Researchers at TUM and the Helmholtz Zentrum München have moved a step closer towards developing innovative drug molecules for the treatment of psychiatric diseases. They discovered how inhibitors inactivate a special protein that plays a key role in various diseases. Their approach can be applied to other medically relevant proteins where the development of specific inhibitors has proved difficult up to now. The research effort was led by Michael Sattler, Director of the Institute of Structural Biology at the Helmholtz Zentrum München and Professor of Biomolecular NMR-Spectroscopy at TUM as well as Principal Investigator at the MSB.

  • Machine learning-based software scGen predicts cell behavior

    AI extrapolates from mice to humans

    The scGen computer model, developed by scientists at the Technical University of Munich (TUM) and Helmholtz Zentrum München, predicts how cells will behave. The software uses artificial intelligence to model the response of a cell to a disease or treatment – with no need for experimental data from pertubed human cells.

  • The Orbem Team. Image: BayStartUP

    MSB start-up wins third prize in Munich Business Plan Competition

    In the Munich Business Plan Competition, the third prize went to the company Orbem, a start-up founded at the Munich School of BioEngineering. Orbem has developed a method for identifying the sex of poultry embryos still in the egg. The first and second spots were also claimed by start-ups incubated at the Technical University of Munich (TUM).

  • Prof. Oliver Lieleg and PhD student Ceren Kimna use balls and pipe cleaners in different colors to visualize how nanoparticles can be bound together by DNA fragments. Such connections may become the basis of drugs that release their active ingredients in sequence. Image: Uli Benz / TUM

    Artificial DNA can control release of active ingredients from drugs

    A drug with three active ingredients that are released in sequence at specific times: Thanks to the work of a team at the Technical University of Munich (TUM), what was once a pharmacologist's dream is now much closer to reality. With a combination of hydrogels and artificial DNA, nanoparticles can be released in sequence under conditions similar to those in the human body.

  • Microelectrode arrays on gelatin: A team surrounding Professor Wolfrum has successfully printed sensors on gummi candy. Image: N. Adly / TUM

    Producing sensors with an inkjet printer

    Microelectrode arrays (MEAs) can be printed on gelatin and other soft materials

    Microelectrodes can be used for direct measurement of electrical signals in the brain or heart. These applications require soft materials, however. With existing methods, attaching electrodes to such materials poses significant challenges. A team at the Technical University of Munich (TUM) has now succeeded in printing electrodes directly onto several soft substrates.