MIBE Seminar: X-ray Dark-Field Computed Tomography at the Human-Scale: Challenges and Implementation of a First Prototype

Topic: X-ray Dark-Field Computed Tomography at the Human-Scale: Challenges and Implementation of a First Prototype

Speaker: Jakob Häusele (Pfeiffer Group)

Date and Time: Tuesday 07 May 2024, 1:00 pm

Abstract: Grating-based X-ray dark-field imaging is an interferometric technique that enables visualization of the alveolar structures in lungs. In the clinical context, the technique has been successfully tested in initial studies with radiographic applications, but has not yet been transferred to computed tomography (CT) imaging. Recently, we presented a first human-scale dark-field CT prototype, which is capable of yielding unobstructed 3D views, that overcomes previous roadblocks with novel design and data processing approaches. With this prototype system, we demonstrated the feasibility to implement a Talbot-Lau interferometer on a clinical CT system (Philips iCT, Philips Healthcare, Cleveland, USA) to perform dark-field imaging with clinical acquisition time and field of view. Here, we give an overview of the project and report on the main challenges during development and how we addressed them.