Topic: Design of Nanostructures as Mammalian Gene Reporters for Electron Microscopy
Speaker: Alberto Piovesan (Westmeyer Group)
Date and Time: Tuesday, 21 December 2021, 1:00 pm
Abstract: Fluorescent reporters like GFP kicked off a new era in biomedical research by enabling easy fusion to a variety of proteins and enzyme targets for multi-color readouts of cellular processes. Still, for imaging at the best resolution achievable today through Electron Microscopy (EM), equally flexible reporters are in comparison yet lacking. Advances in protein structure predictions and design in the recent years have been fuelled by technological breakthroughs, extensive growth of biological databases and increasing availability of computational power. Using such tools we aim to introduce a set of genetically encoded nanostructures that are able to generate geometrically distinct and precise EM contrast.
More information
This semester, the MIBE Seminar will take place online (Zoom). Please register via email (katharina.scholz(at)tum.de) and we are happy to provide the access data.
Further Program Winter Term 2021 / 2022
| 11 January 2022 | 1:00 pm | Hu Peng | Doct. cand. (Wolfrum) | Polyacrylate Heart Three-Dimensional Microelectrode Arrays via Laser-Cutting for Sensoring and Bioelectronics. |
| 18 January 2022 | 1:00 pm | Okan Uelgen | GCB doct. cand. (Ntziachristos) | Optical Detectors of Ultrasound for Optoacoustic Endoscopy. |
| 25 January 2022 | 1:00 pm | Lisa Heck | Doct. cand. (Herzen) | tbd |
| 01 February 2022 | 1:00 pm | Julian Geilenkeuser | Doct. cand. (Westmeyer) | tbd |
| 08 February 2022 | 1:00 pm | Niklas Armbrust | HELENA doct. cand. (Westmeyer) | tbd |
| 08 February 2022 | 1:20 pm | Oleksandr Berezin | Doct. cand. (Westmeyer) | Development and Characterization of Genetically Controllled Reporters for Electron Microscopy and Superresolution Light Microscopy. |
| 15 February 2022 | 1:00 pm | Alessandro Wollek | GCB doct. cand. (Lasser) | Out-of-DIstribution Detection for Clinical Decision Support in Radiology. |